Dr. Bekim Sadikovic is a Professor and Program Head, Molecular Diagnostics Program,
Department of Pathology and Laboratory Medicine - a joint venture between LHSC and St. Joseph's Health Care, London, servicing a wide range of constitutional and oncology molecular genetic diagnostics including Clinical Molecular Genetics, Molecular Pathology, Clinical Cytogenetics, and Biochemical Genetics Laboratories at the Schulich School of Medicine and Dentistry. 

Dr. Sadikovic’s research interests involve applying genomics technologies to clinical diagnostics with particular focus on developing genomic and epigenomic biomarkers in hereditary and acquired genomic conditions. Dr. Sadikovic serves as the Clinical and Scientific Director of the Verspeeten Clinical Genome Centre, and translational genomics facility which focuses on development and clinical implementation of genomic technologies and biomarkers in care of patients with genomic disorders including hereditary genetic conditions and cancer. The Centre utilizes advanced bioinformatic approaches including machine learning on patient’s clinical and genomics data to novel develop diagnostic tool and technologies. This includes machine learning-based algorithms for diagnosis of hereditary genetic disorders based on patient’s epigenomic profiles called EpiSign.

In this week's core session of Grand Rounds, he presents DNA methylation episignatures - a front-line diagnostic for rare disorders?